RP 70676
CAS No. 136609-26-2
RP 70676 ( —— )
Catalog No. M26422 CAS No. 136609-26-2
RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 260 | Get Quote |
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10MG | 430 | Get Quote |
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25MG | 710 | Get Quote |
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50MG | 972 | Get Quote |
|
100MG | 1332 | Get Quote |
|
500MG | 2673 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameRP 70676
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NoteResearch use only, not for human use.
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Brief DescriptionRP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).
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DescriptionRP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).(In Vitro):RP 70676 is a potent rabbit arterial ACAT inhibitor with IC50 of 40 nM and has been shown to be an effective inhibitor of ACAT derived from a number of tissues and species including man. The IC50 values range from 21 nM for hamster liver ACAT to 108 nM for enzyme from the intestine of cholesterol fed rabbits; in human hepatic tissues(IC50 : 44 nM). Murine macrophages the compound has an IC50 of 540 nM in whole cell P388D.(In Vivo):In NZW rabbits,RP 70676 (10 mg/kg, p.o.) is well absorbed with plasma levels.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number136609-26-2
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Formula Weight416.6
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Molecular FormulaC25H28N4S
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1cc(C)n(CCCCCSc2nc(c([nH]2)-c2ccccc2)-c2ccccc2)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ouzir M, Bouhaddou N, Khalki H, Lakhdar-Ghazal N. Physiological and pharmacological properties of 5-methoxytryptophol. Expert Rev Endocrinol Metab. 2013 Jul;8(4):355-364.
molnova catalog
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